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I bought a wrecked Lamborghini Revuelto but ever since owning the car and rebuilding it ive never been able to start it. Lamborghini says it needs a new hybrid battery once the cars been in a accident but cant guarantee that will work so ive got to find a way of getting this car started myself.

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Venture capitalists Jake Gibson (BTV), Masha Bucher (Day One Ventures), Vedika Jain (Weekend Fund) and Elizabeth Yin (Hustle Fund) share insights on navigating the current fundraising climate, emphasizing the complexities of the market. They note that while some companies, particularly in AI, can secure funding easily, others face significant challenges, leading to a bifurcated landscape. The conversation highlights the importance of focusing on product-market fit, understanding customer needs, and maintaining momentum in fundraising efforts. Founders are encouraged to be adaptable, prioritize problem-solving over rigid solutions, and leverage community engagement to enhance visibility. Ultimately, the panel stresses the need for resilience and a strong execution strategy in a fluctuating market.

This was filmed at our annual flagship Startup Grind Conference in Silicon Valley. Next year’s event will take place April 29-30, 2026. Visit https://www.startupgrind.tech and https://www.startupgrind.com for more info.

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Watch my full interview with Dr. Nolan Williams: https://youtu.be/UO7IgQ_x-Qg

This clip is from a very special episode of The Tim Ferriss Show, an episode that might be an example of peeking around corners and catching a glimpse of the future of mental health treatments in the next five to ten years.

The guest is Nolan Williams, MD (@NolanRyWilliams). Nolan is an associate professor within the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine and director of the Stanford Brain Stimulation Lab. He has a broad background in clinical neuroscience and is triple board certified in general neurology, general psychiatry, and behavioral neurology and neuropsychiatry. Themes of his work include examining spaced learning theory and neurostimulation techniques, development and mechanistic understanding of rapid-acting antidepressants, and identifying objective biomarkers that predict neuromodulation responses in treatment-resistant neuropsychiatric conditions.

Nolan specializes in looking at cutting-edge treatments and new technologies that can be applied to treatment-resistant psychiatric disorders—so, treatment-resistant depression, disorders that are notoriously difficult to address, such as OCD, and many others.

Nolan’s work resulted in an FDA clearance for the world’s first noninvasive, rapid-acting neuromodulation approach for treatment-resistant depression. And I’ve tested this myself, and we get into this in the conversation. He has published papers in Brain, American Journal of Psychiatry, and Proceedings of the National Academy of Sciences. Results from his studies have gained attention in Science and NEJM Journal Watch. He has received two NARSAD Young Investigator Awards, the Gerald L. Klerman Award, and the National Institute of Mental Health Biobehavioral Research Award for Innovative New Scientists.

We also discuss things like ibogaine that are seemingly unrelated to neuromodulation, as Nolan is very well-versed in multiple disciplines and in multiple toolkits, both pharmacological and non-invasive neuromodulatory. It’s this combination, actually, this rare Venn diagram, that makes him incredibly interesting to me.

I really enjoyed this conversation. I think it is very important, highly tactical, and I hope you enjoy it as much as I did.

P.S. “Magnesium–Ibogaine Therapy in Veterans with Traumatic Brain Injuries” is now live in Nature Medicine: https://www.nature.com/articles/s41591-023-02705-w

Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors.

Dr. Martha Beck has been called “the best-known life coach in America” by NPR and USA Today. She holds three Harvard degrees in social science and has published nine non-fiction books, one novel, and more than 200 magazine articles. Her recent book, The Way of Integrity: Finding the Path to Your True Self, was an instant New York Times Best Seller.

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Watch the full interview: https://www.youtube.com/watch?v=Ieu68CfTR4g

Links and resources from this episode: https://tim.blog/2024/04/17/martha-beck/

Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 900 million downloads and been selected for “Best of Apple Podcasts” three years running.

Sign up for "5-Bullet Friday" (Tim's free weekly email newsletter): https://go.tim.blog/5-bullet-friday-yt/
Follow the Tim Ferriss Podcast: https://tim.blog/podcast/
Visit the Tim Ferriss Blog: https://tim.blog/
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Dr. Bruce Greyson’s research for the past half century has focused on the aftereffects and implications of near-death experiences and has resulted in more than 100 presentations to national and international scientific conferences, more than 150 publications in academic medical and psychological journals, 50 book chapters, and numerous research grants. He is a co-author After: A Doctor Explores What Near-Death Experiences Reveal about Life and Beyond.

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Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 900 million downloads and been selected for “Best of Apple Podcasts” three years running.

Sign up for "5-Bullet Friday" (Tim's free weekly email newsletter): https://go.tim.blog/5-bullet-friday-yt/
Follow the Tim Ferriss Podcast: https://tim.blog/podcast/
Visit the Tim Ferriss Blog: https://tim.blog/
Follow Tim Ferriss on Twitter: https://twitter.com/tferriss/
Follow Tim Ferriss on Instagram: https://www.instagram.com/timferriss/
Like Tim Ferriss on Facebook: https://www.facebook.com/TimFerriss/

Robert Rodriguez is a film director, screenwriter, producer, cinematographer, editor, and composer. Rodriguez has written, produced, directed, and edited a series of successful films including El Mariachi, Desperado, From Dusk Till Dawn, the Spy Kids franchise, Once Upon a Time in Mexico, Frank Miller’s Sin City, and many more. Robert recently launched Brass Knuckle Films, an investable action film slate: https://brassknucklefilms.com/

This episode is brought to you by:

Cresset prestigious family office for CEOs, founders, and entrepreneurs: https://cressetcapital.com/tim (book a call today)

AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D (and 5 free AG1 travel packs) with your first subscription purchase.)

Wealthfront high-yield cash account: https://Wealthfront.com/Tim (Start earning 4.00% Annual Percentage Yield (APY) on your short-term cash until you’re ready to invest. And when new clients open an account today, you can get an extra fifty-dollar bonus with a deposit of five hundred dollars or more.)

Terms & Conditions apply. APY as of 12/27/24 and is subject to change. Tim Ferriss receives cash compensation from Wealthfront Brokerage, LLC for advertising and holds a non-controlling equity interest in the corporate parent of Wealthfront Brokerage. See full disclosures here.

Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 900 million downloads and been selected for “Best of Apple Podcasts” three years running.

Sign up for "5-Bullet Friday" (Tim's free weekly email newsletter): https://go.tim.blog/5-bullet-friday-yt/
Follow the Tim Ferriss Podcast: https://tim.blog/podcast/
Visit the Tim Ferriss Blog: https://tim.blog/
Follow Tim Ferriss on Twitter: https://twitter.com/tferriss/
Follow Tim Ferriss on Instagram: https://www.instagram.com/timferriss/
Like Tim Ferriss on Facebook: https://www.facebook.com/TimFerriss/

In this episode, Jason chats with David Friedberg—CEO of Ohalo Genetics and co-host of the All-In Podcast—about how AI is transforming agriculture and startups. David introduces Ohalo’s "Boosted Breeding" technology, which enables plants to inherit 100% of genes from both parents, potentially doubling crop yields. They also discuss building AI-first companies, genome language models, and the future of creativity in an AI-driven world.

Timestamps:
(0:00) David Friedberg joins Jason to discuss AI Basics.
(1:44) How AI leveled up hiring and operations at startups
(5:46) AI and economic opportunities, complex problem-solving, and leadership's role
(11:48) How to build an AI-first company culture
(16:48) AI's transformative impact on biology and DNA sequencing
(21:36) The “GLM” - GPT for DNA Is already in production
(23:17) Biology meets AI: designing perfect plants with CRISPR and genome models
(32:08) Is the “Age of Abundance” around the corner?
(35:56) Democratization of creativity through AI: personalized Star Wars musicals & the future of media

Uncover more valuable insights from AI leaders in Google Cloud's 'Future of AI: Perspectives for Startups' report. Discover what 23 AI industry leaders think about the future of AI—and how it impacts your business. Read their perspectives here: https://goo.gle/futureofai

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All rights for the video shared and linked below belong to the original copyright holder, and we are using the footage under the principle of fair use.

Listen here:
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Overcast: https://overcast.fm/itunes315114957/this-week-in-startups-audio

#startups #entrepreneurship #investing #angelinvesting #tech #news #business #AI

Rich Barton is the co-founder and co-executive chairman of Zillow, a company transforming how people buy, sell, rent, and finance homes. Before Zillow, Rich founded Expedia within Microsoft in 1994 and successfully spun the company off as a public company in 1999. He served as president, CEO, and board director of Expedia and later co-founded and served as non-executive chairman of Glassdoor.

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Links to everything discussed:
https://tim.blog/2025/04/17/rich-barton/#content

Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 900 million downloads and been selected for “Best of Apple Podcasts” three years running.

Sign up for "5-Bullet Friday" (Tim's free weekly email newsletter): https://go.tim.blog/5-bullet-friday-yt/
Follow the Tim Ferriss Podcast: https://tim.blog/podcast/
Visit the Tim Ferriss Blog: https://tim.blog/
Follow Tim Ferriss on Twitter: https://twitter.com/tferriss/
Follow Tim Ferriss on Instagram: https://www.instagram.com/timferriss/
Like Tim Ferriss on Facebook: https://www.facebook.com/TimFerriss/

Today’s show: Trump takes aim at Apple with a potential 25% iPhone tariff, Anthropic releases two powerful new Claude models claiming top performance in coding tasks, and two founders go head-to-head in the final round of Founder Fridays. In this packed episode, Jason, Alex, and Lon unpack what Trump’s latest trade threat really means, why Anthropic’s AI progress could reshape the dev landscape, and which startup—an AI ad network or industrial automation platform—comes out on top. A fast-paced look at the volatility, breakthroughs, and ambition defining today’s startup ecosystem.

(0:00) Episode Teaser(3:41) MORE tariffs, this time on Apple… is this just a message to Tim Cook?
(7:08) Potential impact of tariffs on Apple
(10:09) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit http://northwestregisteredagent.com/twist today!
(14:14) Anthropic’s new models are topping the LLM charts but are they REALLY self-aware
(20:07) LinkedIn Ads - Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups
(24:35) Who should buy OnlyFans? Jason, Alex, and Lon each have ideas
(30:03) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist
(35:10) Gut health is important but do we need SMART toilets?
(40:34) Which TWiST 500 companies are blowing up on secondary markets?
(47:27) The Founder Friday city competition FINAL ROUND: see which startup wins!


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Thank you to our partners:

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All rights for the video shared and linked below belong to the original copyright holder, and we are using the footage under the principle of fair use.


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Overcast: https://overcast.fm/itunes315114957/this-week-in-startups-audio

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#startups #entrepreneurship #investing #angelinvesting #tech #news #business

This time, we have a very special episode I recorded with my close friend Kevin Rose. We cover dozens of topics: from the cutting edge of health tech to pro-tips for colonoscopies; AI; adventures in Japan and Taiwan seeking out perfect coffee and tea; tips for drinking less alcohol; powerful documentaries like 32 Sounds and books such as Awareness; the unexpected joys and therapeutic benefits of adult Lego; and much, much more.

This episode is brought to you by:

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Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 900 million downloads and been selected for “Best of Apple Podcasts” three years running.

Sign up for "5-Bullet Friday" (Tim's free weekly email newsletter): https://go.tim.blog/5-bullet-friday-yt/
Follow the Tim Ferriss Podcast: https://tim.blog/podcast/
Visit the Tim Ferriss Blog: https://tim.blog/
Follow Tim Ferriss on Twitter: https://twitter.com/tferriss/
Follow Tim Ferriss on Instagram: https://www.instagram.com/timferriss/
Like Tim Ferriss on Facebook: https://www.facebook.com/TimFerriss/

[00:00] Start.
[00:44] Two old men discuss the importance of regular medical checkups.
[07:29] Zen and the art of 32 Sounds.
[10:34] Going with the low-poly Flow.
[13:49] KevKev goes cleanclean and sober.
[20:57] The first rule of AA is you do not talk about AA.
[22:15] LEGO bricks (and Nanoblocks) as art for grown-ups.
[24:19] Maintaining sobriety with a partner who still drinks.
[27:36] Addressing under-the-hood reasons behind addiction with a group.
[30:05] TimTim talks Taiwan and tea.
[37:45] A Japanese coffee bender.
[43:52] An "expresso" intervention.
[44:54] Where Americans can get Taiwanese tea if they can't make the trip.
[46:10] Kevin's new WHOOP wearable and quantifying health benchmarks/goals.
[52:48] I'm getting a new exercise bike because the old one rubbed me the wrong way.
[54:16] Kevin keeps COVID and cooties at bay with Profi in his schnozz.
[57:09] Sippin' dashi and conquering anxiety with Awareness.
[01:01:42] Getting a (Versa) Gripp on eclectic injuries.
[01:05:20] Finding magic in the ordinary with Paul Madonna and Hayao Miyazaki.
[01:08:36] The Well of Being is back in stock for a reasonable price.
[01:09:18] Finding Asian artisanal goods in the US without having to travel.
[01:12:08] Squirrels: distracting dogs and humans for millennia.
[01:13:29] My personal ups and downs with accelerated TMS.
[01:23:57] The current state of consumer-level sleep aid technology.
[01:29:24] How full genome sequencing helped Kevin tame a once-insurmountable health issue.
[01:31:49] Eyeing traffic at the intersection of AI and life sciences.
[01:34:04] Genetic data privacy concerns.
[01:38:15] Face to face with my deepfaked side hustler.
[01:39:44] Kevin's unsettling AI headphone review experiment and its implications for real humans.
[01:42:42] Steps Kevin has taken toward proving he's a real boy.
[01:44:05] "You were talking to models — you were just talking to large language models."
[01:46:01] Exploding Kittens and I made a game together: Coyote.
[01:47:48] When meditation retreats go right (and wrong).
[01:55:11] Parting thoughts.