Videos

The Trick to Becoming Who You Want to Be

Robert Rodriguez is a film director, screenwriter, producer, cinematographer, editor, and composer. Rodriguez has written, produced, directed, and edited a series of successful films including El Mariachi, Desperado, From Dusk Till Dawn, the Spy Kids franchise, Once Upon a Time in Mexico, Frank Miller’s Sin City, and many more. Robert recently launched Brass Knuckle Films, an investable action film slate: https://brassknucklefilms.com/

This episode is brought to you by:

Cresset prestigious family office for CEOs, founders, and entrepreneurs: https://cressetcapital.com/tim (book a call today)

AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D (and 5 free AG1 travel packs) with your first subscription purchase.)

Wealthfront high-yield cash account: https://Wealthfront.com/Tim (Start earning 4.00% Annual Percentage Yield (APY) on your short-term cash until you’re ready to invest. And when new clients open an account today, you can get an extra fifty-dollar bonus with a deposit of five hundred dollars or more.)

Terms & Conditions apply. APY as of 12/27/24 and is subject to change. Tim Ferriss receives cash compensation from Wealthfront Brokerage, LLC for advertising and holds a non-controlling equity interest in the corporate parent of Wealthfront Brokerage. See full disclosures here.

Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 900 million downloads and been selected for “Best of Apple Podcasts” three years running.

Sign up for "5-Bullet Friday" (Tim's free weekly email newsletter): https://go.tim.blog/5-bullet-friday-yt/
Follow the Tim Ferriss Podcast: https://tim.blog/podcast/
Visit the Tim Ferriss Blog: https://tim.blog/
Follow Tim Ferriss on Twitter: https://twitter.com/tferriss/
Follow Tim Ferriss on Instagram: https://www.instagram.com/timferriss/
Like Tim Ferriss on Facebook: https://www.facebook.com/TimFerriss/


David Friedberg on AI-First Startups & the Future of Biology, Business & Creativity | AI Basics

In this episode, Jason chats with David Friedberg—CEO of Ohalo Genetics and co-host of the All-In Podcast—about how AI is transforming agriculture and startups. David introduces Ohalo’s "Boosted Breeding" technology, which enables plants to inherit 100% of genes from both parents, potentially doubling crop yields. They also discuss building AI-first companies, genome language models, and the future of creativity in an AI-driven world.

Timestamps:
(0:00) David Friedberg joins Jason to discuss AI Basics.
(1:44) How AI leveled up hiring and operations at startups
(5:46) AI and economic opportunities, complex problem-solving, and leadership's role
(11:48) How to build an AI-first company culture
(16:48) AI's transformative impact on biology and DNA sequencing
(21:36) The “GLM” - GPT for DNA Is already in production
(23:17) Biology meets AI: designing perfect plants with CRISPR and genome models
(32:08) Is the “Age of Abundance” around the corner?
(35:56) Democratization of creativity through AI: personalized Star Wars musicals & the future of media

Uncover more valuable insights from AI leaders in Google Cloud's 'Future of AI: Perspectives for Startups' report. Discover what 23 AI industry leaders think about the future of AI—and how it impacts your business. Read their perspectives here: https://goo.gle/futureofai

Check out all of the Startup Basics episodes here: https://thisweekinstartups.com/basics

Check out Google Cloud: https://cloud.google.com/

Check out Ohalo: https://www.ohalo.com/

Follow David:
X: https://x.com/friedberg
LinkedIn: https://www.linkedin.com/in/davidfriedberg/

Follow Jason:
X: https://twitter.com/Jason
LinkedIn: https://www.linkedin.com/in/jasoncalacanis

Follow TWiST:
Twitter: https://twitter.com/TWiStartups
YouTube: https://www.youtube.com/thisweekin
Instagram: https://www.instagram.com/thisweekinstartups
TikTok: https://www.tiktok.com/@thisweekinstartups
Substack: https://twistartups.substack.com

All rights for the video shared and linked below belong to the original copyright holder, and we are using the footage under the principle of fair use.

Listen here:
Apple: https://podcasts.apple.com/us/podcast/this-week-in-startups-audio/id315114957
Spotify: https://open.spotify.com/show/6ULQ0ewYf5zmsDgBchlkr9
Overcast: https://overcast.fm/itunes315114957/this-week-in-startups-audio

#startups #entrepreneurship #investing #angelinvesting #tech #news #business #AI


"How I Got in the Best Shape of My Life at 57” — Expedia Founder Rich Barton

Rich Barton is the co-founder and co-executive chairman of Zillow, a company transforming how people buy, sell, rent, and finance homes. Before Zillow, Rich founded Expedia within Microsoft in 1994 and successfully spun the company off as a public company in 1999. He served as president, CEO, and board director of Expedia and later co-founded and served as non-executive chairman of Glassdoor.

This episode is brought to you by:

Ramp easy-to-use corporate cards, bill payments, accounting, and more: https://ramp.com/tim (Get $250 when you join Ramp)

Cresset prestigious family office for CEOs, founders, and entrepreneurs: https://cressetcapital.com/tim (book a call today)

Shopify global commerce platform, providing tools to start, grow, market, and manage a retail business: https://shopify.com/tim (one-dollar-per-month trial period)

Links to everything discussed:
https://tim.blog/2025/04/17/rich-barton/#content

Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 900 million downloads and been selected for “Best of Apple Podcasts” three years running.

Sign up for "5-Bullet Friday" (Tim's free weekly email newsletter): https://go.tim.blog/5-bullet-friday-yt/
Follow the Tim Ferriss Podcast: https://tim.blog/podcast/
Visit the Tim Ferriss Blog: https://tim.blog/
Follow Tim Ferriss on Twitter: https://twitter.com/tferriss/
Follow Tim Ferriss on Instagram: https://www.instagram.com/timferriss/
Like Tim Ferriss on Facebook: https://www.facebook.com/TimFerriss/


Apple’s Tariff Trouble, Anthropic’s New Models, and Our Founder Friday Finale | E2130

Today’s show: Trump takes aim at Apple with a potential 25% iPhone tariff, Anthropic releases two powerful new Claude models claiming top performance in coding tasks, and two founders go head-to-head in the final round of Founder Fridays. In this packed episode, Jason, Alex, and Lon unpack what Trump’s latest trade threat really means, why Anthropic’s AI progress could reshape the dev landscape, and which startup—an AI ad network or industrial automation platform—comes out on top. A fast-paced look at the volatility, breakthroughs, and ambition defining today’s startup ecosystem.

(0:00) Episode Teaser(3:41) MORE tariffs, this time on Apple… is this just a message to Tim Cook?
(7:08) Potential impact of tariffs on Apple
(10:09) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit http://northwestregisteredagent.com/twist today!
(14:14) Anthropic’s new models are topping the LLM charts but are they REALLY self-aware
(20:07) LinkedIn Ads - Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups
(24:35) Who should buy OnlyFans? Jason, Alex, and Lon each have ideas
(30:03) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist
(35:10) Gut health is important but do we need SMART toilets?
(40:34) Which TWiST 500 companies are blowing up on secondary markets?
(47:27) The Founder Friday city competition FINAL ROUND: see which startup wins!


Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

Check out the TWIST500: https://www.twist500.com

Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp


Links from episode:
Throne One: https://www.thronescience.com/product?
Arcana: https://arcana.ad/
TACTUN: https://tactun.com/


Follow Lon:
X: https://x.com/lons


Follow Alex:
X: https://x.com/alex
LinkedIn: https://www.linkedin.com/in/alexwilhelm


Follow Jason:
X: https://twitter.com/Jason
LinkedIn: https://www.linkedin.com/in/jasoncalacanis

Thank you to our partners:

(10:09) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit http://northwestregisteredagent.com/twist today!

(20:07) LinkedIn Ads - Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups

(30:03) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist


All rights for the video shared and linked below belong to the original copyright holder, and we are using the footage under the principle of fair use.


Listen here:
Apple: https://podcasts.apple.com/us/podcast/this-week-in-startups-audio/id315114957
Spotify: https://open.spotify.com/show/6ULQ0ewYf5zmsDgBchlkr9
Overcast: https://overcast.fm/itunes315114957/this-week-in-startups-audio

More from us:
Twitter: https://twitter.com/twistartups
Instagram: https://www.instagram.com/thisweekinstartups
Official site: https://thisweekinstartups.com

Subscribe to our YouTube to watch all full episodes:
https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A?sub_confirmation=1

Subscribe to TWiST Clips for all the best moments:
https://www.youtube.com/channel/UCS7tJlcUA6PzVHEMo-X7ddg?sub_confirmation=1

#startups #entrepreneurship #investing #angelinvesting #tech #news #business


The Random Show — New Health Gadgets, How to Drink Less, AI + Genome, and More

This time, we have a very special episode I recorded with my close friend Kevin Rose. We cover dozens of topics: from the cutting edge of health tech to pro-tips for colonoscopies; AI; adventures in Japan and Taiwan seeking out perfect coffee and tea; tips for drinking less alcohol; powerful documentaries like 32 Sounds and books such as Awareness; the unexpected joys and therapeutic benefits of adult Lego; and much, much more.

This episode is brought to you by:

Vanta trusted compliance and security platform: https://vanta.com/tim ($1000 off)

Momentous high-quality supplements: https://livemomentous.com/tim (code TIM for up to 35% off)

ExpressVPN high-speed, secure, and anonymous VPN service: https://www.expressvpn.com/tim (get 3 or 4 months free on their annual plans)

Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 900 million downloads and been selected for “Best of Apple Podcasts” three years running.

Sign up for "5-Bullet Friday" (Tim's free weekly email newsletter): https://go.tim.blog/5-bullet-friday-yt/
Follow the Tim Ferriss Podcast: https://tim.blog/podcast/
Visit the Tim Ferriss Blog: https://tim.blog/
Follow Tim Ferriss on Twitter: https://twitter.com/tferriss/
Follow Tim Ferriss on Instagram: https://www.instagram.com/timferriss/
Like Tim Ferriss on Facebook: https://www.facebook.com/TimFerriss/

[00:00] Start.
[00:44] Two old men discuss the importance of regular medical checkups.
[07:29] Zen and the art of 32 Sounds.
[10:34] Going with the low-poly Flow.
[13:49] KevKev goes cleanclean and sober.
[20:57] The first rule of AA is you do not talk about AA.
[22:15] LEGO bricks (and Nanoblocks) as art for grown-ups.
[24:19] Maintaining sobriety with a partner who still drinks.
[27:36] Addressing under-the-hood reasons behind addiction with a group.
[30:05] TimTim talks Taiwan and tea.
[37:45] A Japanese coffee bender.
[43:52] An "expresso" intervention.
[44:54] Where Americans can get Taiwanese tea if they can't make the trip.
[46:10] Kevin's new WHOOP wearable and quantifying health benchmarks/goals.
[52:48] I'm getting a new exercise bike because the old one rubbed me the wrong way.
[54:16] Kevin keeps COVID and cooties at bay with Profi in his schnozz.
[57:09] Sippin' dashi and conquering anxiety with Awareness.
[01:01:42] Getting a (Versa) Gripp on eclectic injuries.
[01:05:20] Finding magic in the ordinary with Paul Madonna and Hayao Miyazaki.
[01:08:36] The Well of Being is back in stock for a reasonable price.
[01:09:18] Finding Asian artisanal goods in the US without having to travel.
[01:12:08] Squirrels: distracting dogs and humans for millennia.
[01:13:29] My personal ups and downs with accelerated TMS.
[01:23:57] The current state of consumer-level sleep aid technology.
[01:29:24] How full genome sequencing helped Kevin tame a once-insurmountable health issue.
[01:31:49] Eyeing traffic at the intersection of AI and life sciences.
[01:34:04] Genetic data privacy concerns.
[01:38:15] Face to face with my deepfaked side hustler.
[01:39:44] Kevin's unsettling AI headphone review experiment and its implications for real humans.
[01:42:42] Steps Kevin has taken toward proving he's a real boy.
[01:44:05] "You were talking to models — you were just talking to large language models."
[01:46:01] Exploding Kittens and I made a game together: Coyote.
[01:47:48] When meditation retreats go right (and wrong).
[01:55:11] Parting thoughts.


Trump Threatens 25% Tariff on Apple iPhones 🇺🇸📱

Trump threatens Apple with a 25% tariff if iPhones aren’t made in the U.S.—but moving the supply chain is nearly impossible.

#Apple #Trump #iPhone #Tariffs #TechNews #SupplyChain #Manufacturing #TWIST


How Pro Athletes Heal Tendon Injuries 25% Faster

Dr. Keith Baar is a Professor at the University of California, Davis in the Department of Physiology and Membrane Biology. During his Ph.D. studies, his research revealed that mechanical strain on muscle fibers activates the mammalian target of rapamycin (mTOR) signaling pathway, a crucial regulator of muscular hypertrophy. Subsequently, he studied the molecular dynamics of skeletal muscle adaptation to endurance training under the guidance of Dr. John Holloszy, a legend in the field of exercise physiology, considered the father of modern exercise biochemistry. Building on all of this experience, he conducted research into tendon health and the potential for engineering ligaments, which could have implications for treatment and recovery from injuries.

This episode is brought to you by:

Cresset prestigious family office for CEOs, founders, and entrepreneurs: https://cressetcapital.com/tim (book a call today)

AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D (and 5 free AG1 travel packs) with your first subscription purchase.)

Shopify global commerce platform, providing tools to start, grow, market, and manage a retail business: https://shopify.com/tim (one-dollar-per-month trial period)

*

Links to everything discussed: https://tim.blog/2025/02/26/dr-keith-baar/

Tim Ferriss is one of Fast Company’s “Most Innovative Business People” and an early-stage tech investor/advisor in Uber, Facebook, Twitter, Shopify, Duolingo, Alibaba, and 50+ other companies. He is also the author of five #1 New York Times and Wall Street Journal bestsellers: The 4-Hour Workweek, The 4-Hour Body, The 4-Hour Chef, Tools of Titans and Tribe of Mentors. The Observer and other media have named him “the Oprah of audio” due to the influence of his podcast, The Tim Ferriss Show, which has exceeded 900 million downloads and been selected for “Best of Apple Podcasts” three years running.

Sign up for "5-Bullet Friday" (Tim's free weekly email newsletter): https://go.tim.blog/5-bullet-friday-yt/
Follow the Tim Ferriss Podcast: https://tim.blog/podcast/
Visit the Tim Ferriss Blog: https://tim.blog/
Follow Tim Ferriss on Twitter: https://twitter.com/tferriss/
Follow Tim Ferriss on Instagram: https://www.instagram.com/timferriss/
Like Tim Ferriss on Facebook: https://www.facebook.com/TimFerriss/


Humans Will Be Begging for Work Soon 😳🤖

AI agents will soon complete tasks before you’re done asking—humans will be begging for work.

#AI #FutureOfWork #Anthropic #Automation #TechNews #Startups #TWIST


Inside the Shady World of Startup Secondaries 💸📉

Startup secondaries are booming—but behind the scenes, SPVs, markups, and boiler room tactics are getting sketchy.

#Startups #SecondaryMarket #VC #Investing #Finance #SPV #TechNews #TWIST